Animal Subjects

ERIK, Office of the Attending Veterinarian Guideline, Revised 07/2025 Buprenorphine ER-LAB (Bup ER) is an extended-release analgesic compounded by Wedgewood that lasts ~48 hours in mice and rats. ULAR staff can administer Bup ER for researchers when... Read More

IACUC Policy: 043-05, Effective Date: 07/13/2012, Last Revision: 05/17/2024 Overview/Purpose USDA covered species may be placed under anesthesia for a variety of reasons including performance of procedures, survival surgery, or imaging. Animals... Read More

IACUC Policy: 006-06, Effective Date: 01/25/2008, Last Revision: 11/17/2023 Overview/Purpose Blood collection/sampling is a common and important procedure utilized in the research setting. This policy provides guidance on blood collection... Read More

IACUC Policy: 007-08, Effective Date: 11/18/2005, Last Revision: 06/20/2025 Overview/Purpose The purpose of this policy is to ensure compliance with the Guide regarding space requirements for mice and rats utilized for breeding activities in an... Read More

IACUC Policy: 034-06, Effective Date: 06/01/2009, Last Revision: 03/17/2023 Overview/Purpose Carbon dioxide (CO2) gas is frequently used to euthanize rodents in a research setting. CO2 is introduced into a cage or space in a controlled manner to... Read More

ERIK, Office of the Attending Veterinarian Guideline 19-020, Revised 11/27/2019 Preparation It is important to understand that for most of these methods to be effective, gross debris such as blood or other organic matter must be removed prior to... Read More

IACUC Policy: 044-06, Effective Date: 01/18/2013, Last Revision: 04/18/2025  Overview/Purpose The Institutional Animal Care and Use Committee (IACUC) requires documentation of animal care procedures and verification of environmental... Read More

IACUC Policy: 003-05, Effective Date: 10/2002, Last Revision: 02/21/2025 Overview/Purpose Federal regulations require the Institutional Animal Care and Use Committee (IACUC) to consider the number of animals proposed as part of the protocol review... Read More

IACUC Policy: 046-02, Effective Date: 05/17/2013, Last Revision: 06/17/2016, Last Reviewed: 04/18/2025 Overview/Purpose The American Veterinary Medical Association (AVMA) guidelines for the euthanasia of animals provides limited recommendations... Read More

IACUC Policy:  033-04, Effective Date: 04/18/2008, Last Revision: 05/17/2024 Overview/Purpose Certain experimental paradigms require the use of food or water restriction. Restriction of food or fluid for experimental purposes requires... Read More

Species Specific Examples of Enclosures Rodents: Microisolator cage with lid secured in place, within an opaque container (e.g. a Rubbermaid® tub, zippered pillowcase, reusable grocery bag or other bag that closes/ties shut) or completely... Read More

IACUC Policy: 005-07, Effective Date: 10/2002, Last Revision: 11/15/2024 Overview/Purpose The university maintains an occupational health and safety program as an essential part of the overall program of animal care and use. All IACUC protocols... Read More

IACUC Policy: 042-04, Effective Date: 03/18/2011, Last Revision: 08/16/2024 Overview/Purpose Federal regulations do not permit an Institutional Animal Care and Use Committee (IACUC) member to participate in the review of research in which he/she... Read More

IACUC Policy: 049-05, Effective Date: 08/16/2013, Last Revision: 03/17/2023 Overview/Purpose To ensure animal safety and reduce risk of anesthetic gas exposure to animals and personnel, proper maintenance of anesthesia equipment, appropriate waste... Read More

IACUC Policy: 055-03, Effective Date: 04/19/2019, Last Revision: 04/18/2025 Overview/Purpose Social housing and environmental enrichment are addressed at the level of the individual housing area due to the size and scope of the program at The Ohio... Read More

IACUC Policy: 051-05, Effective Date: 10/28/2013, Last Revision: 05/17/2024 Overview/Purpose The Institutional Animal Care and Use Committee (IACUC) must oversee the methods used to transport animals outside the approved housing locations to... Read More

IACUC Policy: 011-04, Effective Date: 10/2002, Last Revision: 05/18/2018, Last Reviewed: 11/15/2024 Overview/Purpose The Institutional Animal Care and Use Committee (IACUC) is responsible for reviewing the use of live vertebrate animals used in... Read More

IACUC Policy: 024-04, Effective Date: 10/2002, Last Revision: 11/17/2023 Overview/Purpose The purpose of this policy is to define what the OSU IACUC considers prolonged restraint and thereby requires additional justification and description in the... Read More

ERIK, Office of the Attending Veterinarian Guideline, Revised 11/27/2019 Introduction According to the Guide for the Care and Use of Laboratory Animals, “Refrigerated storage, separated from other cold storage, is essential for storage of... Read More

IACUC Policy: 052-03 Effective Date: 10/18/13 Last Revision: 02/17/2023  Overview/Purpose The Institutional Animal Care and Use Committee (IACUC) must be made aware of conditions that have the potential to negatively impact animal welfare.... Read More