How do I access the Huron system?
How do I find a submission in the Huron system?
When searching for a study in Huron, select the IRB tab, then click the "Submissions" tab across the top menu bar, then select "All Submissions" in the table below. You can use the Wildcard (%) symbol before typing in the study number, PI name, or study title, if you do not know the exact match for your search. You can change the search type in "Filter by". For example, if you are looking for STUDY20250011 you can type in "%20250011" or "%0011" and it will bring up any study containing those numbers to narrow the search.
How do I navigate back to the main study page from a modification or continuing review submission?
You will find the main study page as a link in the clickable pathway above the title of the modification or continuing review. Click on the study title to navigate to the main study landing page.
How do I submit a new initial study in the Huron system?
How do I obtain the required departmental approval for new initial submissions?
My submission is stuck in departmental review. Who do I contact to check on this?
Departmental review and sign-off is required before a new non-exempt study can be submitted to the IRB. You can reach out to the departmental endorser identified in the verification message.
If a study has been stuck for more than 2 weeks in department review, you may need to reset the departmental review assignment created for the reviewer. To do so, uncheck the box for “I certify that this submission is ready to be routed for departmental approval” on the submission’s Departmental Approval page, click Save or Continue, and then Exit to close the form. In 1-2 hours, the departmental endorsement assigned to the approver will be voided in DocuSign and removed from the system. After this is done, follow the original process to check the box for “I certify that this submission is ready to be routed for departmental approval” on the submission’s Departmental Approval page, click Save or Continue, and then Exit to close the form. A new departmental review assignment will then be created.
If you still experience issues with a departmental review, contact the Office of Research Help Desk at orhelpdesk@osu.edu.
My submission was routed to the incorrect departmental endorser. How can this be corrected?
If the departmental endorsement DocuSign envelope is sent to the wrong person, the envelope can be reassigned to the correct person by logging into docusign.com and using the reassignment feature. This action will allow the immediate envelope to be signed by the correct endorser without additional delays. Instructions for reassignment are available on the DocuSign support pages.
Departmental review assignments will be managed by IRB staff until an appropriate designation in Workday can be created to allow for departmental management of these endorsers. Please email orhelpdesk@osu.edu with any changes to the departmental endorser list if you experience an assignment that needs to be updated. Be sure to include the lastname.# of the individuals to be added or removed, as well as what department or college they should be assigned to. Requests will be validated to ensure their appropriateness before being processed.
Are there differences between terminology used in Buck-IRB compared to Huron?
Yes. The chart below outlines the differences (bolded) and similarities.
Old (Buck-IRB) | → | New (Huron) |
---|---|---|
IRB Protocol Analyst | → | IRB Coordinator |
Draft application | → | Pre-Submission |
ORRP Staff Screening | → | Pre-review |
Incomplete | → | Clarification Requested |
Amendment | → | Modification Request (from PI) |
Continuing Review | → | Continuing review |
Expedited Review | → | Designated Review |
Convened Review | → | Committee Review |
Modifications Required | → | Modifications Required (from IRB) |
Deferral | → | Deferral |
Event Report (ER) | → | Reportable New Information (RNI) |
How do I check the status of my Huron submission? What do the different statuses mean?
The large orange box in the top left corner of the main study page will tell you the current status of your study. For continuing reviews and modifications, you must be in the specific continuing review or modification submission to check the status.
What do I need to know about my existing study that migrated from Buck-IRB?
What do I need to know about my legacy study that did not migrate because it was approved by one of the Ohio State IRBs before Buck-IRB was implemented in 2014?
What do I need to know about my legacy study that did not migrate because it was ceded to an external IRB before Buck-IRB was implemented in 2014?
What do I need to know about my exempt study that did not migrate?
Exempt studies will remain active in Buck-IRB until the study expires (3 years after the initial exempt determination) and will automatically close in Buck-IRB. If revisions are needed to an exempt study that was originally approved in Buck-IRB, a new exempt application must be submitted in the Huron system. All new exempt determinations will be made in Huron.
Will minimal risk research that qualifies for expedited review still require an annual status report (ASR) submission after the transition to Huron?
No, minimal risk research currently undergoing administrative review (i.e., ASR) will not require annual submissions in Huron. Instead, the Huron system will issue annual automatic notifications to investigators about the need to submit modifications (previously known as amendments) and Reports of New Information (previously known as event reports). Minimal risk research that currently requires continuing review will still require continuing review in the Huron system.
How do I reply to pre-review comments and requests for revisions?
Once you are ready to submit your response to comments/revisions:
How do I submit a continuing review for a ceded/external study?
You do not need to submit continuing review applications for studies reviewed by an external IRB. You also do not need to submit continuing review approval notifications for ceded studies.
On the Basic Study Information page, it asks me if this study is a multi-site/collaborative study or a single-site study. My study involves other sites, but how do I know which to pick?
When should I submit a request to rely on an external IRB?
For studies where Ohio State is a participating site (pSite), requests to rely on an external IRB should be submitted after the reviewing IRB (sIRB) has approved the study.
How do I request to rely on an external IRB?
Complete the New Study SmartForm in the Huron system, indicate that an external IRB will serve as the IRB of record, and attach all requested materials. The PI can submit the smart form by clicking the "Submit" activity. Maintain electronic copies of all information submitted to the external IRB in case revisions are required.
How do I request an Ohio State IRB to serve as the single IRB of record (sIRB) for my collaborative or multi-site research study?
On the New Study SmartForm, indicate if the study is a multi-site or collaborative research study, then select "Yes" to the question "Will your IRB act as the single IRB of record for other participating sites?" Complete the rest of the SmartForm and attach all required materials. Participating sites are added separately by executing the "Add Participating Site" activity. The PI can submit the SmartForm by clicking the "Submit" activity. The participating sites will not be able to reach final approval (i.e., be declared active) until the initial main application for Ohio State is approved.
What are PI proxies and primary contacts?
Will I still need to complete CITI courses to be involved in human subjects research?
Yes, Ohio State requires that all active researchers maintain current CITI training in both Human Subjects Protection (HSP) and Responsible Conduct of Research (RCR). All Ohio State study personnel can log into CITI with their institutional credentials. HSP training is valid for a three-year period and RCR training is valid for a four-year period. After those periods pass, the courses must be repeated.
Generally, it takes up to 24 hours for information to update in the Huron system after training has been completed; however, updates may be delayed in certain rare circumstances. If you do not see updated training information in Huron after 2 business days, please contact ORHelpDesk@osu.edu and provide a copy of the appropriate completion certificate(s). New studies cannot be submitted if either of the required courses are not current for all study team members. If you submit a modification or a continuing review where training is not current, the application will be sent back to you.
Does a lapsed Conflict of Interest (COI) disclosure impact the ability to submit in the Huron system the way it did in Buck-IRB?
Yes, lapsed COI disclosures will impact the PI's ability to submit initial review applications. If you submit a modification or a continuing review in which COIs are not current, the application will be sent back to you via a clarification request.
How do I check CITI training and COI disclosure status for me and my study team?
Can administrative staff be listed as additional contacts as they are in the Buck-IRB system?
No, the Huron system does not have a role designated for additional contacts. The Huron system allows for only one primary contact. If the PI chooses to designate an individual or individuals to submit incomplete responses and responses to IRB modifications on their behalf, they must be listed as either a co-investigator, key personnel, or regulatory staff on the study and the PI would need to designate them as a PI Proxy. All co-investigators, key personnel, regulatory staff, and PI proxies must comply with institutional requirements (i.e., CITI HSP and RCR courses, and a conflict-of-interest disclosure). Please see CITI FAQ for more details.
What options are available for “Role in research” when adding study team members?
The possible roles are “Co-investigator,” “Key Personnel,” and “Regulatory Staff.”
Can I upload password-protected documents or zip files to the Huron system?
No, please avoid uploading password-protected documents or zip files to the system.
Article ID: 95
Created: February 27, 2025
Last Updated: April 11, 2025
Online URL: https://ohiostateresearch.knowledgebase.co/article/huron-irb-system-faqs-95.html